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KMID : 1159320160180030353
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Korean Journal of Vision Science
2016 Volume.18 No. 3 p.353 ~ p.360
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Risk Factors for Age-Related Macular Degeneration in Korean : 2011, 2012 Based on National Health and Nutrition Examination Survey Analysis
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An Hea-Young
Lee Eun-Hee
Lee Koon-Ja
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Abstract
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Purpose: Based on the National Health and Nutrition Examination Survey information in the period of 2011 and 2012, the risk factors for age-related macular degeneration (AMD) in Korea were analyzed.
Methods: We analyzed the National Health and Nutrition Examination Survey, the fifth edition of 2011 and 2012, that subjects consist of adults who got health screens and eye examinations in order to find the risk factors of AMD. Risk factors that are correlated with AMD were analyzed using logistic regression analysis with and without adjusting for sex and age factors and the significance level was set less than 0.05.
Results: In the demographical and public health aspect, aged population and habitants of rural area and population of lower educational level indicated higher incidence rate of AMD in the analysis without adjusting age and gender. With adjusting age and gender, analysis of AMD are highly correlated in women and population of low educational level. In physiological and epidemiological aspect, hypertension, hyperlipidemia, hypercholesterolemia, and triglyceride level
were increased risk for AMD in without adjusting age and gender, however after adjusting age and gender there was no correlation between AMD and physiological factor. Without adjusting age and gender, eye diseases of family history, astigmatism, hyperopia were related to AMD, however after adjusting age and gender myopia was low risk factor for AMD and hyperopia and cataracts was high risk factors. As physical circumstances in pre-condition only sun exposure for more than 5 hours was correlated to AMD as in after adjusting age and gender smoking and sun exposure for more than
5 hours were high risk factors with high incident rate causing AMD.
Conclusions: It has confirmed that AMD is closely related to age and gender. In particular, after adjusting age and gender, hyperopia, cataracts, smoking and sun exposure increase probability of the AMD.
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KEYWORD
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National Health and Nutrition Examination Survey, Age-related Macular Degeneration, Gender, Age, Risk factors
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